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germ-free [ˈdʒɜːrmfriː, ˈdʒɜːmfriː] PRID.

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The mice can be treated in the same standards as germfree mice, such as sterilized water, germfree environment, and careful handling. en.wikipedia.org

He selected for the bacteria that dominated and can be isolated in culture, and then colonized germfree mice with different bacteria combinations. en.wikipedia.org

Germfree mice are not a good representation of normal mice, with issues of enlarged cecum, low reproductive rates, poorly developed immune system, and reduced health. en.wikipedia.org

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