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ribonucleotide SAM.

Geslo uporabnika

- Uredi geslo
- Predlagaj za brisanje

ribonucleotide biochemia

rybonukleotyd m. spol

Enojezični primeri (nepregledani od uredništva PONS)

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Other polymerases have been "engineered" for particular properties by mutating specific functional sites so that, for example, dideoxyribonucleotides or ribonucleotides can be incorporated during the primer extension step. www.genengnews.com

Some examples of enzymes characterized in this way are: ribonucleotide reductase methane monooxygenase, tryptophan dioxygenase, deoxypusine hydroxylase, protocatechuate 2,3 dioxygenase, and cytochrome ba3. en.wikipedia.org

These ribonucleotide changes are likely to be harmful, as their ribose 2-hydroxyl group increases susceptibility of the adjacent phosphodiester bond to hydrolysis. en.wikipedia.org

To do this, they used genetic engineering to create a strain of mice whose cells produced higher-than-normal levels of an enzyme called ribonucleotide reductase. www.washington.edu

Hydrolysis of the phosphate bonds generates the ribonucleotide guanine mono-phosphate and a modified 2-pyridone. en.wikipedia.org

The reduction of ribonucleotides to deoxyribonucleotides is catalyzed by ribonucleotide reductase. en.wikipedia.org

This conversion is catalysed by ribonucleotide reductase (see figure). en.wikipedia.org

All ribonucleotide reductase enzymes use a common sulfhydryl radical mechanism reliant on reactive cysteine residues that oxidize to form disulfide bonds in the course of the reaction. en.wikipedia.org

Depending on the allosteric configuration, one of the four ribonucleotides binds to the active site. en.wikipedia.org

However, it was subsequently reported in 2009 that activated pyrimidine ribonucleotides can be synthesized under plausible prebiotic conditions. en.wikipedia.org

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