He is given credit for the first description of acute, chronic, endemic and epidemic, and use terms such as, exacerbation, relapse, resolution, crisis, paroxysm, peak, and convalescence.
Other frequent side effects include skin dryness, pruritus, nausea, photodrug reactions (including popular acne medications used by teens), disease exacerbation and disease induction.
Possible side effects include abdominal pain, allergy, diarrhea, headache, hepatic dysfunction/hepatitis, nausea or vomiting, exacerbation of porphyries, pruritis, rash, somnolence, vertigo, or dizziness.
