Other causes of aortic stenosis include calcification of a congenital bicuspid aortic valve (30-40% of cases) and acute rheumatic fever post-inflammatory (less than 10% of cases).
Deaths from typhoid fever, rheumatic fever, diphtheria, appendicitis, influenza, and tuberculosis fell dramatically, which the average life expectancy increased.
Her thesis focused on the study of clinical and anatomical pathology of fatal forms of rheumatic fever (rheumatic endocarditis) due to streptococcus infection.
The relation to rheumatic fever was strengthened by many studies that showed that women with normal pregnancies before rheumatic fever developed chorea in subsequent pregnancies.